Journal: Diagnostics

Article Title: The Effect of Lesion Length on Doppler Velocities Used Routinely to Determine Carotid Stenosis Cross-Sectional Severity

doi: 10.3390/diagnostics15101259

Figure Lengend Snippet: Quantitative measurements of the lesion length and IVUS evaluation of minimal lumen area. ( A ) Carotid artery catheter angiography in a symptomatic lesion. ( B ) Quantitative angiography measurement of the total lesion length and stenosis severity by % diameter stenosis. ( C ) Quantitative angiography measurement of the length of stenotic segment with cross-sectional severity of at least 50% diameter stenosis (DS). ( D ) IVUS evaluation (in this case, under proximal neuroprotection by transient flow reversal) of the minimal lumen cross-sectional area. Arrows indicate, respectively, total lesion length ( B ) and the length of stenotic segment with cross-sectional severity of ≥50% diameter stenosis ( C ). RD is the reference diameter. Diameter stenosis (%) was calculated according to the NASCET method ; cf., .

Article Snippet: Results : IVUS imaging (20 MHz Volcano/Philips) was uncomplicated.

Techniques:

Journal: Diagnostics

Article Title: The Effect of Lesion Length on Doppler Velocities Used Routinely to Determine Carotid Stenosis Cross-Sectional Severity

doi: 10.3390/diagnostics15101259

Figure Lengend Snippet: Combined effect of lesion length and cross-sectional stenosis severity on flow velocities in carotid stenotic lesions. Graphs on the left ( A , C , E ) show a combined effect of LL and MLA on PSV whereas those on the right ( B , D , F ) demonstrate a combined effect of LL and MLA on EDV. In ( A , B ) the LL is indexed to MLA by IVUS; in ( C , D ) the MLA is estimated from conventional quantitative angiography measurements, whereas in ( E , F ) the MLA is automatically determined from the minimal contrast column density in the stenotic segment in relation to that in the reference segment. Note that the correlation coefficients in ( E , F ) nearly reach those in ( A , B ), consistent with a greater accuracy of MLA determination via the automatic densitometric measurement rather than estimation from a conventional (planar) contrast angiography. See text for details. PSV—peak systolic velocity, EDV—end-diastolic velocity, LL—total lesion length, IVUS-MLA—intravascular ultrasound minimal lumen area. QA-MLA—minimal lumen area estimation from conventional (planar) quantitative angiography; QA DENSITOM -MLA—quantitative angiographic densitometric (contrast column density-based) minimal lumen area, n—number.

Article Snippet: Results : IVUS imaging (20 MHz Volcano/Philips) was uncomplicated.

Techniques:

Journal: Diagnostics

Article Title: The Effect of Lesion Length on Doppler Velocities Used Routinely to Determine Carotid Stenosis Cross-Sectional Severity

doi: 10.3390/diagnostics15101259

Figure Lengend Snippet: Relationship between planar angiographic and IVUS measurement of D min and cross-sectional stenosis severity. Histogram ( A ) and Bland–Altman presentation ( B ) demonstrate systematic underestimation of D min by angiographic measurement, with mean absolute difference (Abs D) of −0.39 mm and mean relative difference (Rel D) of −22.5%. This, along with inability of the planar angiogram–based estimation to correct for any non-circular lumen (example in D), results in a systematic overestimation of cross-sectional stenosis severity (mean Abs D in area stenosis of 13.4%; ( C ) with a rather wide data scatter on Bland–Altman analysis ( D ). AS CIRC —circular estimation of cross-sectional carotid stenosis severity based on angiographic measurement of reference diameter and minimal lumen diameter, AS IVUS —intravascular ultrasound (IVUS) measurement of area stenosis (AS), QA—quantitative angiography, D min —minimal lumen diameter.

Article Snippet: Results : IVUS imaging (20 MHz Volcano/Philips) was uncomplicated.

Techniques: